![2024-08-30 JASIS](https://www.protochips.com/wp-content/uploads/2024/08/2024-08-30-JASIS-150x150.png)
Visit our Booth at JASIS (5B-703) in Tokyo Japan
August 30, 2024
Protochips is proud to host Prof. Deb Kelly and Dr. Mike Casasanta of The Kelly Lab located at the Center for Structural Oncology at Penn State for a webinar surrounding critical COVID-19 research completed with the Protochips Poseidon Select in situ Liquid Cell System for TEM.
As described by The Kelly Lab:
Liquid-Phase Electron Microscopy (LP-EM) is an exciting new area in the materials imaging field providing unprecedented views of molecular processes. Time-resolved insights from LP-EM studies are a strong complement to the remarkable results achievable with cryo-EM. Here, we will present new high-resolution structures and dynamic insights of human viruses contained in liquid droplets. We used gene therapy viral vectors as a model system due to their structural stability and potential as vaccine candidates for COVID-19. Improving our understanding of the physical properties of biological entities in a liquid state, as maintained in the human body, has broad societal implications for human health and disease.
As a complement to these results, we recently determine the first cryo-EM structure of the SARS-CoV-2 Nucleocapsid (N) protein. A novel antibody-binding site in the N structure revealed a hidden target that is 100% conserved in all SARS-CoV-2 variants of concern. This information may prove useful in developing next-generation therapies to battle COVID-19.
June 8, 2021 8:00 am PDT, 11:00 am EDT, 5:00 pm CET
REGISTER TODAY!