New Avenues for Capturing Mineralization Events at Biomaterial Interfaces with Liquid-Transmission Electron Microscopy

Tuesday publication post! In this new publication from #McMasterUniversity in Canada, Liza-Anastasia DiCecco, JingZhang, Travis Casagrande and Kathryn Grandfield have looked at new methods to observe mineralization events at biomaterial interfaces using the #PoseidonAX system!

Liquid-transmission electron microscopy (liquid-TEM) opens up new possibilities for observing mineralization events at biomaterial interfaces, an area with vast potential yet largely unexplored. In this paper, a novel method to visualize calcium phosphate (CaP) nucleation and assembly on titanium (Ti) surfaces.

By combining nanofabrication of Ti lamellae with focused ion beam (FIB) techniques and in situ liquid-TEM, the authors captured multiphasic CaP particles nucleating, adhering, and forming assemblies at the Ti interface in real-time.

This approach offers groundbreaking insights into the nanoscale interactions between biomaterials and liquids.

Want to read the whole paper?
https://www.doi.org/10.1038/s41467-024-46842-3

Want to know more about our Poseidon AX solution for biological materials?
https://www.protochips.com/solutions/by-applications/biological-materials/

#Protochips #FindYourBreakthrough #InSituMicroscopy #MineralizationEvents #InSituLiquidPhase