In situ transmission electron microscopy (TEM) is a technique that allows researchers to study materials in realistic conditions while taking advantage of the resolving power of a TEM to understand structure-function relationships. These systems are designed to expand the capabilities of traditional vacuum TEM by adding stimuli such as heating and biasing in addition to environments such as gases or liquids.

All our in situ TEM solutions are integrated with our patented AXON machine vision software platform, enabling researchers of all TEM skill levels to acquire impactful, high quality in situ results in less time than systems without the same machine vision capability. Each solution extends beyond the microscope, including tools for sample preparation, data collection, and data management and processing to support rigor, reproducibility and efficiency.

Do you want to know more about the advantages of in situ TEM research? Click here for some background information.

In Situ Gas Cell

Atmosphere AX introduces realistic, environmental temperatures and pressures inside the TEM, enabling you to image materials and processes in relevant conditions.

Click here to learn more about Atmosphere AX

In Situ Heating and Biasing

Fusion AX precisely controls thermal and electrical processes within the electron microscope, allowing you to explore behaviors at high temperature and under electrical stresses

Click here to learn more about Fusion AX

TEM Data Correlation

Data management is becoming a larger issue in the world, Protochips has focussed on solutions to make data management easy for electron microscopy.

Click here to learn more about our TEM data correlation software

In Situ Liquid Cell Solutions

Protochips offers two product families for performing liquid-based studies within the TEM:

Triton AX is the first heating and cooling liquid electrochemical system for TEM, offering a wide temperature range of -50 °C to 300 °C to be applied to electrochemical experiments. Study battery materials, electrocatalysts, corrosion processes, and nanomaterial synthesis at relevant temperatures during electrochemical measurements to understand the impact temperature has on performance. In addition, use the cooling function to minimize electron beam damage on sensitive materials.

Poseidon AX is the original Protochips liquid cell, ideal for characterizing materials in their liquid environment where additional stimuli is not needed, performing electrochemical experiments at room temperature, or studying materials at elevated temperatures, up to 100°C, for a broad range of research areas. Poseidon AX also offers the ability to mix liquids for biomineralization and chemistry studies where the mixing of liquid is important to the process being studied.

Heating & Cooling with Electrochemistry

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Mixing with Heating or Electrochemistry

Click here to learn more about Poseidon AX

RDM and FAIR

Publishing research data using Findable, Accessible, Interoperable, and Reusable (FAIR) principles is becoming increasingly important particular when applying for funding.


Click here to find out why